Infertility isn’t always about low sperm count or motility—sometimes, the problem lies deep within the sperm’s DNA. One such lesser-known yet significant issue is Sperm DNA Fragmentation (SDF), a condition increasingly recognized as a key factor in male infertility.
At Aashakiran IVF Pvt. Ltd., North India’s most trusted and fastest-growing IVF chain, we focus on advanced diagnostics like SDF testing to uncover hidden causes of infertility and offer personalized, evidence-based treatments.
What is Sperm DNA Fragmentation?
Sperm DNA fragmentation refers to breaks or damage in the genetic material (DNA) within the sperm cell. Even when a semen analysis shows normal count, motility, and morphology, damaged DNA can impact fertilization, embryo development, and even lead to miscarriage.
Causes of Sperm DNA Fragmentation
There are many factors that can lead to sperm DNA damage:
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Oxidative stress due to infections or inflammation
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Lifestyle factors like smoking, alcohol, obesity, or stress
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Advanced paternal age
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Exposure to environmental toxins or heat
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Varicocele (enlarged veins in the scrotum)
Impact on Fertility
High sperm DNA fragmentation can result in:
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Poor fertilization rates
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Poor embryo quality
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Recurrent implantation failure
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Increased risk of miscarriage
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Reduced success in IVF/ICSI treatments
How is SDF Tested?
At Aashakiran IVF, we use advanced techniques such as:
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SCSA (Sperm Chromatin Structure Assay)
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TUNEL assay
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COMET assay
These tests help us evaluate the integrity of the sperm DNA, even when standard semen reports are normal.
Treatment & Management at Aashakiran IVF
Under the expert guidance of Dr. Asmita Mahla (Medical Director, 20+ years experience) & Dr. Shivani (Gynae) and our skilled team at Aashakiran centers in Kharar, Ludhiana, Amritsar, and Bathinda, we provide:
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Lifestyle modification plans
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Antioxidant therapy
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Treatment for infections or varicocele
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Testicular sperm retrieval (TESA) for IVF/ICSI
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Advanced sperm selection techniques like MACS & PICSI
When Should You Consider SDF Testing?
We recommend SDF testing if:
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You’ve had multiple IVF/ICSI failures
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There’s unexplained infertility
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There’s a history of recurrent miscarriage
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The male partner is over 40 years of age
Aashakiran IVF – Bringing Clarity to Infertility
At Aashakiran IVF Pvt. Ltd., we believe in diagnosing right to treat right. Sperm DNA fragmentation testing is one of the many ways we ensure accurate diagnosis and targeted treatment, improving your chances of successful conception and healthy pregnancy.
📞 Need to talk? Call us: 872-8080-222
📍 Visit our centers: Kharar | Ludhiana | Amritsar | Bathinda
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🌐 Learn more: www.aashakiranivf.com
Because every couple deserves the joy of parenthood — with science, support, and Aashakiran IVF by your side. 🌈